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Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine 4TFA Synonyms

SKU: 35118147705

4.3
USD195.00 USD224.00

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Description

Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine 4TFA Synonyms CAS Number Related CAS 19479-83-5 Molecular Formula C10H22N4 Molecular Weight 198

85 SMILES: Cl

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H112FN11O27 Molecular Weight 1738

As a negative control

Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrO2 Molecular Weight 218

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine 4TFA SynonymsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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