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Product Name Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C76H106FN9O24 Molecular Weight 1548
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation
Product Name Lenalidomide-5'-CO-PEG6-C2-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C28H43ClN4O10 Molecular Weight 631
diAcFAM is typically supplied as a cell-permeable ligand that
Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414
Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-PNP mal-hexanoyl Product Name Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
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