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The water soluble 5-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group
297 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
When the probe binds to its cellular targets
Excitation maximum = 500 nm
NBD-TM proved to be the most rapid scavenger of HOCl when compared with boronate- and aminophenyl-based fluorogenic probes in a study for monitoring the chlorinating activity of Myeloperoxidase (MPO)
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan texas red The water soluble 5-FAM PEG3SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by
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